MAPT and Alzheimer disease: Moreover, in the same paper, the AUC for discriminating AD-dem patients and controls adjusted for demographic features was 0.79 for plasma NfL (as measured with the same ELISA kit transferred onto the ultrasensitive single-molecule array platform Simoa), 0.85 for CSF total tau (t-tau), 0.81 for CSF phosphorylated tau (p-tau), and 0.64 for plasma tau [44].