INS and Hyperammonemia: BCAA and carbohydrate administration are common nutritional strategies used in an attempt to alleviate central fatigue, though these interventions present certain deleterious effects, such as hyperammonemia (BCAA supplementation) and increased insulin release, augmenting the muscle uptake of BCAA (carbohydrate supplementation) [6,13,18,42,43,44,45,46].