Of note, familial OC index patients with an additional OC family history show a considerably higher BRIP1 mutation prevalence (OR = 32.21, 95% CI = 15.06–68.90, P < 0.0001; Table 1) than familial OC index patients with a BC-only family history (OR = 16.01, 95% CI = 7.82–23.76, P < 0.0001; Table 1). The gene discussed is BRIP1; the disease is breast cancer.