However, the NfL × Aβ42/p-tau ratio best distinguished FTLD from other NDs (AD and DLB) (AUC 0.900 ± 0.025) and especially FTLD from AD (AUC 0.975 ± 0.011) (see Additional file 1: Table S2). The gene discussed is MAPT; the disease is Lewy body dementia.