Apart from OSCC, UCA1 also plays a pivotal role in hypopharyngeal squamous cell carcinoma; with the initial trial confirming its positive correlation with the LNM of hypopharyngeal squamous cell carcinoma, the UCA1 loss-of-function test in Fadu cells validated its role in driving invasion [58], whereas further mechanistic study is required to elucidate the phenotype. Here, UCA1 is linked to hypopharynx squamous cell carcinoma.