IDH1 and astrocytoma (excluding glioblastoma): The prognosis of patients varies greatly depending on clinical factors (tumor size, patient’s age) and the molecular subtype, oligodendroglioma: mutant for isocitrate dehydrogenase 1 or 2 (IDH1 or 2; IDHmt) with co-deletion of the chromosomal arms 1p and 19q (codel); or astrocytoma: with (IDHmt), or without IDH mutation (IDH wild type) [7, 18, 36, 48].