TGFB1 and lung cancer: Although we did not observe that HOXC8 affected the expression of N-cadherin or cadherin-11, we demonstrated that HOXC8 expression markedly decreased E-cadherin expression and increased vimentin and TGFβ1 expression in lung cancer cells, indicating that HOXC8 plays an important role in the EMT process of lung cancer cells.