CFH and age-related macular degeneration: To further investigate this issue, we first analyzed the SNPs of CFH in our patients, and found that the GG genotype in the p.I62V polymorphism was significantly associated with an increased risk of AMD [Odds ratio (OR) = 6.88, 95% confidence interval (CI) = 2.03–23.29], whereas no association was found with the p.Y402H polymorphism (Supplementary Table S1).