In addition, overexpression of TMEM170B significantly slowed the cell migration and invasion of breast cancer cells in vitro (Fig. 4c and Supplementary Fig. 3c), while miR-27a inhibitor prevented the cell migration, invasion, and wound-healing mediated by TMEM170B overexpression in MDA-MB-231 cells (Fig. 4d and Supplementary Fig. 3d and f). This evidence concerns the gene TMEM170B and breast cancer.