The mRNA levels of interferons (beta interferon [IFN-β] and IFN-γ), proinflammatory cytokines (tumor necrosis factor [TNF], interleukin-1β [IL-1β], IL-12, and IL-23), chemokines (MIP2, MCP1, and CXCL10), Th1-associated genes (IFN-γ, t-bet), T-reg-associated genes (Foxp3), inflammasome components (NLRP3, caspase-1), T cell markers (CD4 and CD8), and iNOS enzyme were measured in the brains of MALT1+/+ or MALT1−/− mice at different time points after infection and compared to mRNA levels in the corresponding uninfected controls. The gene discussed is CASP1; the disease is infection.