Considering that EZH2 is involved in STK39 regulation and considering that a recent study showed STK39 to be repressed by DNA hypermethylation in B cell lymphoma (40), we assessed whether DNA methyltransferases were involved in the EBNA3A-mediated silencing of STK39 in LCLs. Here, EZH2 is linked to B-cell non-Hodgkin lymphoma.