In this study, we studied expression of p65 and p‐p105 (precursor p50) in 186 patients with resectable NSCLC and found that co‐expression of p65 and p‐p105 but not p65 or p‐p105 alone was an independent prognosis biomarker. This evidence concerns the gene NFKB1 and non-small cell lung carcinoma.