CYP19A1 and breast carcinoma: Mean CYP19A1 expression levels were found to be significantly elevated in breast tumor tissue samples of patients with an age at breast cancer onset ≥ 50 years (1.9-fold; P = 0.007; Fig. 3a) and in postmenopausal patients (1.7-fold; P = 0.047; Fig. 3b).