The same picture occurred for CD8+ cells at villous tip, where celiac disease exhibited a higher density (22.8 ± 5.9 cells/100 enterocytes) than NCGS and negative controls (9.0 ± 4.6 and 10.0 ± 2.6 cells/100 enterocytes, resp., p < 0.001) as displayed in Figure 3(b). This evidence concerns the gene CD8A and celiac disease.