To investigate the clinical relevance of this newly discovered mTOR regulation of PGAM1 in human cancer tissues, we analyzed The Cancer Genome Atlas (TCGA) RNAseq datasets for correlation between PGAM1 expression and mTOR signaling pathway activity in the tumors of 1016 NSCLC patients with Gene Set Enrichment Analysis (GSEA). The gene discussed is MTOR; the disease is non-small cell lung carcinoma.