However, as shown in Fig. 6g, 81% of samples with low CCND1 expression exhibited high levels of miR-374a (22/27 cases), whereas 35% of samples with high CCND1 expression had low expression of miR-374a (19/54 cases) in early stage of NSCLC specimens (Stages I–II) (P = 0.0164). Here, CCND1 is linked to non-small cell lung carcinoma.