TNFSF10 and neoplasm: In contrast, mice treated with an oncolytic adenovirus (H5CmTERT-Ad or H5CmTERT-Ad/TRAIL) had a significantly reduced tumour area in comparison with those treated with PBS; H5CmTERT-Ad and H5CmTERT-Ad/TRAIL caused 61.7% and 89.8% suppression, respectively (P < 0.01 for H5CmTERT-Ad, P < 0.001 for H5CmTERT-Ad/TRAIL versus PBS).