TNFSF10 and neoplasm: Importantly, H5CmTERT-Ad/TRAIL induced potent tumour growth inhibition up to 21 days post cell injection in U87MG/Fluc orthotopic glioblastoma tumour model (P < 0.01 for H5CmTERT-Ad/TRAIL versus PBS) (Fig. 8a and b), showing similar results as those observed in Figs 5 and 7.