MECOM and acute myeloid leukemia: To explore whether AML precursors have an aberrant cell division pattern, we crossed Tet2−/−;Flt3ITD mouse to Evi1-GFP mouse, harvested GFP+ cells from Tet2−/−;Flt3ITD;Evi1-GFP mouse bone marrow and examined the phenotypic HSCs by flow cytometry.