We were able to show that Gal-8 expression is a positive prognostic factor for overall and disease-free survival of ovarian cancer patients, while Gal-9 expression determines overall and disease-free survival in two different ways: Moderate Gal-9 expression correlates with a reduced survival, compared to Gal-9 negative cases, while patients with high Gal-9 expression showed the best outcome. The gene discussed is LGALS8; the disease is ovarian cancer.