CD44 and ovarian carcinoma: Compared to their CD117-negative counterparts, ovarian cancer CD44+/CD117+ TICs isolated from patient ascites were found to express a third TIC marker, ALDH1A, and to overexpress proteins involved in five major metabolic pathways: OXPHOS, β-oxidation, glucose uptake, the pentose phosphate pathway (PPP) and the TCA cycle [101].