Consistent with a recent study (Teshima et al., 2016), the expression pattern of Fgfr2b and Fgf10 in the embryonic thyroid indicated that the Fgf10-Fgfr2b signaling pathway likely regulates thyroid organogenesis rather than being required for thyroid specification and early thyroid development, as suggested from previous observations of thyroid agenesis in Fgf10-deficient mice (Ohuchi et al., 2000). Here, FGF10 is linked to hypothyroidism, congenital, nongoitrous, 2.