MAD2L2 and colorectal carcinoma: Moreover, the Kaplan–Meier survival analysis of 100 CRC patients showed that high levels of MAD2L2 predicted favorable prognosis (Fig. 1F), high expression of NCOA3 was associated with poor prognosis (Fig. 1G), and patients with high MAD2L2 combined with low NCOA3 had the best outcome, whereas patients with low MAD2L2 combined with high NCOA3 had the worst outcome (Fig. 1H).