Histological analysis revealed similar levels of glomerulosclerosis in both diabetic WT and Hmox1+/− groups (Figure 2(a)) (32.4 ± 9.2% versus 37.3 ± 7.6% of glomeruli with mesangial expansion) and no difference in tubular injury and tubulointerstitial fibrosis. The gene discussed is HMOX1; the disease is glomerulosclerosis.