For instance, the N-glycosylation of the fragment-crystallizable (Fc) portion of immunoglobulin G (IgG) shows to differ in galactosylation, bisection, and fucosylation (17–23), and the acute-phase protein alpha-1-acid glycoprotein (also known as orosomucoid) shows differences in antennarity (i.e., the ratio between di-, tri-, and tetraantennary glycans) and fucosylation with RA as well as changes throughout pregnancy (24, 25). Here, ORM1 is linked to rheumatoid arthritis.