These molecules are subject to extensive modification in cancer, often with marked alterations in the phosphatidylcholine (PC) and phosphatidylethanolamine (PE) metabolism due to changes in the activity of degradative enzymes, including phospholipase A (7, 8) and anabolic enzymes, especially fatty acid synthase, stearoyl-CoA desaturase (SCD) and choline kinase α (9, 10). Here, FASN is linked to cancer.