KCNJ10 and temporal lobe epilepsy: Moreover, association of single nucleotide polymorphisms (SNPs) of KCNJ10 with temporal lobe epilepsy (TLE) accompanying febrile seizures (Heuser et al., 2010) and down-regulation of the Kir4.1 expression in seizure focus specimens from TLE patients (Das et al., 2012; Heuser et al., 2012; Steinhäuser et al., 2012) were also reported.