FOLH1 and Familial prostate cancer: To target prostate-specific membrane antigen (PSMA), Moon et al. [42] encapsulated IONP with amphiphiles containing PEG, DOTA, and PSMA-targeting ligand and radiolabeled them with 68Ga. In vivo PET and MR imaging experiments in mouse prostate cancer xenograft models revealed specific probe accumulation at tumor site.