ITGAM and experimental autoimmune encephalomyelitis: Ganciclovir (GCV), a nucleoside prodrug analogue of ACV, was recently reported to be a potent inhibitor of microglial proliferation that effectively inhibited experimental autoimmune encephalomyelitis (EAE) by reducing the infiltration of CD11b+ CD45high Iba+ macrophages and T cells into the CNS [61].