BCL10 and acute lymphoblastic leukemia: Analysis of the substrates of the MALT1 para-caspase activity in the Jurkat T-ALL model system including CYLD1, BCL10 and RelB revealed a distinct attenuated proteolysis of all tested MALT1 substrates upon GSK3β inhibition either by pharmacological inhibition with SB21 or SB41, or by specific shRNA (Figs 1, 3A–C).