In accordance to the results shown in Fig. 5, inhibition of GSK3β by SB21 (Fig. 6A, lanes 3 + 4) or the shRNA-mediated knock down of IKK2 (Fig. 6A, lanes 1 + 3 and 5 + 7) diminished the P/I-induced BCL10 phosphorylation in metabolically labelled Jurkat T-ALL cells. This evidence concerns the gene BCL10 and acute lymphoblastic leukemia.