TNFSF13B and systemic lupus erythematosus: The relative independence of NZB/W F1 mice from BAFF for the lupus phenotype can be explained by the fact that NZB/W F1 mice SLE pathogenesis is linked to major histocompatibility complex class II (MHCII) locus and pathogenic autoantibody production is primarily dependent on CD4+ T cells61.