To solidify the observed in vivo efficacy of p-niclosamide on CML, we employed the BaF3-T315I-BCR-ABL cells expressing firefly luciferase (BaF3-T315I-BCR-ABL-Luc) cells to visualize the growth by in vivo luminescence imaging with Xenogen IVIS Spectrum. This evidence concerns the gene BCR and chronic myelogenous leukemia, BCR-ABL1 positive.