Furthermore, we examined the mRNA expression of TACC3 and E2F1 in public data sets including expression data of bladder cancer cell lines from Cancer Cell Line Encyclopedia (CCLE)33, RNA-seq data from the study by Guo et al. and found a positive correlation between TACC3 and E2F1 mRNA level (Fig. 4g, h). The gene discussed is E2F1; the disease is cancer.