SOD1 and amyotrophic lateral sclerosis: We thus determined the amount, by Western blot (Fig. 7a–e) and ELISA (Fig. 7g) methods, of sulfenic acid-modified wild-type SOD1 in CSF from 15 patients with sporadic ALS (ages 42–63, mean ± SD 50.3 ± 6.0) and 6 age-matched non-ALS control patients (ages 50–64, mean ± SD 53.5 ± 4.8).