For example, a TF namely ZNF423 is connected with Joubart’s Syndrome in human, and TF namely SP1 is associated with “Disrupt in early Huntington’s disease” in human, whereas hsa-miR-34c-5p is responsible for Bipolar disorder and Schizophenia in human, and miR-524-5p is associated with Amyotrophic lateral sclerosis in human. The gene discussed is ZNF423; the disease is amyotrophic lateral sclerosis.