The 6-month extension period for SORELLA 1 demonstrated that similar glycemic control was maintained with SAR-Lis and Ly-Lis at similar insulin dosages over 1 year.8 Changes from baseline to study end in the daily mealtime and basal insulin dose were small and similar for the two treatment groups within both studies.8,9 Hypoglycemia and TEAEs did not differ between groups in either study.8,9. This evidence concerns the gene INS and Hypoglycemia.