Studies have shown that Celastrol has a pharmacological effect of inhibiting NF-κB, which is involved in the regulation of genes expression that promote the growth and metastasis of tumor (Zhou et al., 2011; Sha et al., 2014), as anti-apoptotic proteins Bcl-2 (Sethi et al., 2013; Lu et al., 2015) and proteases MMP-9 (Kim et al., 2009; Mi et al., 2014). This evidence concerns the gene NFKB1 and neoplasm.