Among the SNV top-ranked promoters (DMD), DHS elements (LRMP) and enhancers (PAX5, BACH2, BCL2, CXCR4, and BCL7A) are highly cancer-type-specific cases with many BCL or CLL mutations (Figs. 2a 4–10, b, 3). The gene discussed is PAX5; the disease is cancer.