TGFB1 and early-onset autosomal dominant Alzheimer disease: The analysis of the pathways yields six pathways associated to seven genes: “Alzheimer disease-presenilin” (P00004), “CCKR signaling map2 (P06959), “Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction” (P00028), “Nicotinic acetylcholine receptor signaling” (P00044), “Ornithine degradation” (P02758), and “TGF-β signaling” (P00052) (Fig. 2b).