Moreover, although khdrbs1 KO male mice showed male infertility, behavioral deficits and poor motor control (Ehrmann et al., 2013), khdrbs2 KO mice as well as khdrbs1 and khdrbs2 double KO mice both exhibited defects in cerebellar morphogenesis (Iijima et al., 2014), and khdrbs3 KO mice displayed synaptic plasticity and behavioral defects (Traunmüller et al., 2016). Here, KHDRBS1 is linked to male infertility.