Although differences were not significant, the CD4 T-cell compartment showed a prompt increase in the resting phenotypes (TN and central memory T cells [TCM]) and a decrease in the effector phenotypes [TEM and effector RA+ T cells ([TEMRA)] at M2 (Figure 3A) compared to HIV-uninfected, that normalized several months after infection. The gene discussed is CD4; the disease is infection.