Analysis of the distribution of CRP genotypes revealed that the CRP rs1130864 A allele carrier state (homozygous and compound heterozygous combination) was significantly more frequent in BD patients with thyroid disorders than in those without (rs1130864 AA + AG vs. GG others: 64.1% vs 50.1%, p = 0.023, pc = 0.046; OR = 1.78, 95% CI = 1.08–2.96), the difference relatively more pronounced among females (rs1130864 AA + AG vs. GG: 69.6% vs 50.4%, p = 0.005, pc = 0.01; OR = 2.25, 95% CI = 1.27–4.04 in female patients, respectively, with and without thyroiditis) (Table 2). Here, CRP is linked to thyroid gland disorder.