A previous study compared survival after ZIKV infection in two mouse models, IFN-α/β and IFN-γ receptor knockout AG129 and SCID32, and found that AG129 mice survived 18.5 days while SCID mice survived 40 days following an identical infection of 2 × 103 PFU/ml. Here, IFNA1 is linked to Zika virus infectious disease.