DISC1 and psychiatric disorder: The most studied are disrupted in schizophrenia one (DISC1 gene) identified by cloning the breakpoints of a balanced 1 : 11 chromosomal rearrangement associated with multiple cases of mental illness including SCZ in a large Scottish pedigree [10], chromosome 22 deletion syndrome associated with a range of severe neurodevelopmental disorders [11], fragile × syndrome [12], Rett syndrome [13] and rare cases of ASD with mutations of neuroligin genes [14].