DICER1 and viral infectious disease: To determine the impact of viral infection on the stability of the LGP2–Dicer complex, we expressed FLAG‐LGP2 in HEK293 cells and infected these with the single‐stranded positive‐strand RNA virus encephalomyocarditis virus (EMCV), a member of the picornaviridae that generates long dsRNA products that trigger type I IFN induction via MDA5 (Pichlmair et al, 2009).