Celiac disease is now defined as a genetically predisposed systemic autoimmune condition characterized by the presence of a variable combination of gluten-dependent enteropathy, other clinical manifestations, and CD-specific antibodies such as anti-tissue transglutaminase antibodies 2 (TG2-IgA and TG2-IgG) and anti-endomysial antibodies (EMAs) [1] . Here, TGM2 is linked to celiac disease.