After glioma C6 cells were transfected withmiR-17 mimics (50 nM) for 72 h, the protein expression of Cyclin D1 (p < 0.001), p-AKT (p < 0.001) and AKT (p < 0.05) decreased compared to Lipofectamine and negative control groups (Fig 7). Here, CCND1 is linked to central nervous system cancer.