The relatively high prevalence of these other species in these sore throat patients support previous studies which have implicated species such as Prevotella melanogenica (along with Fn) in recurrent tonsillitis.[29] The Fn positive_high group had significantly higher scores than those for the entire sore throat patient cohort (1.64 ± 1.05, p = 0.0002), the Fn positive_low patients (nonzero OTU values ≤ 0.1) (1.58 ± 1.04, p = 0.0002), or the Fn negative patients (1.61 ± 0.99, p = 0.0004). This evidence concerns the gene FN1 and medical procedure.