When the study population was stratified into two groups, with and without liver cirrhosis (Table 1), age, the proportions of male gender, diabetes, and on-going AVT, total bilirubin level, and LS value were significantly higher in patients with liver cirrhosis than in those without it, whereas serum albumin level, aspartate aminotransferase (AST) level, ALT level, the proportion of HBeAg positivity, HBV DNA level, and platelet count were significantly lower in patients with liver cirrhosis (all P < 0.05). The gene discussed is ALB; the disease is cirrhosis of liver.