The results found a significant relationship between TMN stage and PVT1 expression in gastric cancer (OR = 2.54, 95% CI: 1.70–3.79), hepatocellular carcinoma (OR = 1.75, 95% CI 1.05–2.90) and lung cancer (OR = 3.62, 95% CI 2.00–6.54). The gene discussed is PVT1; the disease is lung cancer.