Furthermore, 12 studies comprising 1173 patients were pooled to evaluate the association between lymph node metastases and PVT1 expression in different cancers, such as gastric cancer (n = 5), lung cancer (n = 4), colorectal cancer (n = 1), pancreatic cancer (n = 1) and bladder cancer (n = 1). Here, PVT1 is linked to familial pancreatic carcinoma.