MET and head and neck squamous cell carcinoma: Many studies in HNSCC have suggested that c-Met expression is correlated with clinicopathological parameters indicative of poor prognosis, such as differentiation [39], T classification [25, 41, 44], LN metastasis [25, 30, 33, 35, 37–39], disease stage [25, 32, 35], and worse DFS [24, 37, 41, 42] or OS [24, 31, 34, 35, 37, 38, 42].